Article
Sequence variants in the transforming growth beta-induced factor (TGIF) gene are not associated with high myopia.
Investigative ophthalmology & visual science - 1 Jul 2004
Scavello Genaro S, Paluru Prasuna C, Ganter William R, Young Terri L
Abstract excerpt
PURPOSE: High myopia is a common complex-trait eye disorder, with implications for blindness due to increased risk of retinal detachment, macular degeneration, premature cataracts, and glaucoma. Mapping studies have identified at least four loci for nonsyndromic autosomal dominant high myopia at 18p11.31, 12q22-q23, 17q21-q23, and 7q36. The smallest haplotyped interval for these loci is that of the MYP2 locus on...
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