Article
Molecular investigation of the stromal cell-derived factor-1 chemokine in lymphoid leukemia and lymphoma patients from Brazil.
Blood cells, molecules & diseases - 1 Jan 2000
de Oliveira Cavassin Gabriela Gonçalves, De Lucca Fernando Luiz, Delgado André Nayara, Covas Dimas Tadeu, Pelegrinelli Fungaro Maria Helena, Voltarelli Júlio César, Watanabe Maria Angelica Ehara
Abstract excerpt
The stromal cell-derived factor-1 (SDF-1) gene contains a common polymorphism, termed SDF1-3'A, in an evolutionarily conserved segment of the 3'-untranslated region (3'-UTR). We compared SDF-1 genotypes in patients diagnosed with lymphoid leukemias and lymphomas. Since the SDF1-3'A variant deletes the MspI restriction site, PCR-restriction fragment length polymorphism (RFLP) analysis was used for identification...
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