Article
The SDF-1 3'A genetic variation is correlated with elevated intra-tumor tissue and circulating concentration of CXCL12 in glial tumors: a study on Iranian anaplastic astrocytoma and glioblastoma multiforme patients.
Journal of molecular neuroscience : MN - 1 Jun 2013
Moosavi Seyyed Reza, Khorramdelazad Hossein, Amin Masoud, Fatahpoor Shirin, Moogooei Mozhgan, Karimabad Mojgan Noroozi, Paghale Mohamadreza Jamali, Vakilian Alireza, Hassanshahi Gholamhossein
Abstract excerpt
Immunological factors are important in pathogenesis of various malignancies, including neural cancers. The CXC chemokine CXCL12 is involved in the immune responses. Therefore, the aim of the present study was to investigate the association between tumor tissue and circulating concentrations of CXCL12 as well as its genetic variation at position +801 known as(the SDF-1 3'A), in Iranian patients suffering from...
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