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Novel hepatitis B virus surface antigen mutations associated with occult genotype B hepatitis B virus infection affect HBsAg detection.

Journal of viral hepatitis - 1 Sept 2020

Wang Hao, Wang Min, Huang Jieting, Xu Ru, Liao Qiao, Shan Zhengang, Zheng Yourong, Rong Xia, Tang Xi, Li Tingting, Wang Wenjing, Li Chengyao, Fu Yongshui

Abstract excerpt

The causative factors of occult hepatitis B infection are complicated and not yet been fully elucidated. Mutations in hepatitis B virus (HBV) S gene are one of the factors may contributing to occult infection. In this study, 89 blood donors with genotype B occult HBV infection were investigated. Fifty-seven hepatitis B surface antigen (HBsAg)-positive/HBV DNA-positive blood donors served as control group for...

Topics

DNA, Viral
Genotype
Hep G2 Cells
Hepatitis B
Hepatitis B Surface Antigens
Hepatitis B virus
Humans
Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 32336003
DOI: 10.1111/jvh.13309

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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