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Article

Increased seizure susceptibility and cortical malformation in beta-catenin mutant mice.

Biochemical and biophysical research communications - 23 Jul 2004

Campos Victor E, Du Mengyuan, Li Yuqing

Abstract excerpt

Beta-catenin has been implicated in epilepsy because of its altered post seizure expression and the role of Wnt2 signaling in autism. To determine beta-catenin's role in seizure susceptibility, we injected penetylenetetrazol intraperitoneally in beta-catenin cerebral cortex- and hippocampus-specific knockout mice. We then analyzed the latency, number, and duration of four phases of seizure behaviors: (I)...

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Identifiers

PMID: 15219872
DOI: 10.1016/j.bbrc.2004.05.204

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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