The Ami-AliA/AliB Permease of <i>Streptococcus pneumoniae</i> Is Involved in Nasopharyngeal Colonization but Not in Invasive Disease

Abstract excerpt

The Ami-AliA/AliB oligopeptide permease is an ATP-binding cassette transporter which is found in Streptococcus pneumoniae and which is involved in nutrient uptake. We investigated the role of the three paralogous oligopeptide-binding lipoproteins AmiA, AliA, and AliB by using murine models of pneumococcal colonization and invasive disease. A series of mutants lacking aliA, aliB, and amiA either alone or in...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bacterial Infections and Vaccines
• Share to Pneumocystis jirovecii pneumonia detection and treatment
• Share to Pneumonia and Respiratory Infections