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Identification of colonisation and virulence determinants of <i>Streptococcus pneumoniae</i> via experimental evolution in mouse infection models

2020-09-08

Abstract excerpt

Streptococcus pneumoniae is a commensal of the human nasopharynx and a major cause of respiratory and invasive disease. Pneumococcus stimulates upper respiratory tract inflammation that promotes shedding from mucosal surfaces and transmission to new hosts. Colonisation and transmission are partially antagonistic processes. Adhesion to surfaces and evasion of host responses favours the former, whilst detachment, pr...

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Identifiers and source

Literature Corpus work
8e56223d-961e-56e8-8d01-dbb9c56d7f9c
DOI
10.1101/2020.09.08.287698
Open publication

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Identification of colonisation and virulence determinants of <i>Streptococcus pneumoniae</i> via experimental evolution in mouse infection modelsDOI 10.1101/2020.09.08.287698
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