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Identification of radiation-sensitive mutants in the Medaka, Oryzias latipes.

Mechanisms of development - 1 Jul 2004

Aizawa Kouichi, Mitani Hiroshi, Kogure Nozomi, Shimada Atsuko, Hirose Yukihiro, Sasado Takao, Morinaga Chikako, Yasuoka Akihito, Yoda Hiroki, Watanabe Tomomi, Iwanami Norimasa, Kunimatsu Sanae, Osakada Masakazu, Suwa Hiroshi, Niwa Katsutoshi, Deguchi Tomonori, Hennrich Thorsten, Todo Takeshi, Shima Akihiro, Kondoh Hisato, Furutani-Seiki Makoto

Abstract excerpt

We screened populations of N-ethyl-N-nitrosourea (ENU)-mutagenized Medaka, (Oryzias latipes) for radiation-sensitive mutants to investigate the mechanism of genome stability induced by ionizing radiation in developing embryos. F3 embryos derived from male founders that were homozygous for induced the mutations were irradiated with gamma-rays at the organogenesis stage (48hpf) at a dose that did not cause...

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PMID: 15210194
DOI: 10.1016/j.mod.2004.04.002

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RIC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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