Article
The adiponectin gene SNP+45 is associated with coronary artery disease in Type 2 (non-insulin-dependent) diabetes mellitus.
Diabetic medicine : a journal of the British Diabetic Association - 1 Jul 2004
Lacquemant C, Froguel P, Lobbens S, Izzo P, Dina C, Ruiz J
Abstract excerpt
BACKGROUND: The ACRP30/adiponectin gene on chromosome 3q27, a region linked to the metabolic syndrome, encodes for the abundant adipocyte-specific secreted protein. Consistent rodent and human studies suggested that this adipokine may be a molecular link between metabolic and cardiovascular diseases. AIMS: In order to investigate the role of single nucleotide polymorphisms (SNPs) within the APM1 gene in the...
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