Article
The +276 G/T single nucleotide polymorphism of the adiponectin gene is associated with coronary artery disease in type 2 diabetic patients.
Diabetes care - 1 Aug 2004
Bacci Simonetta, Menzaghi Claudia, Ercolino Tonino, Ma Xiaowei, Rauseo Anna, Salvemini Lucia, Vigna Carlo, Fanelli Raffaele, Di Mario Umberto, Doria Alessandro, Trischitta Vincenzo
Abstract excerpt
OBJECTIVE: Two single nucleotide polymorphisms (SNPs) at the adiponectin locus (+45T>G and +276G>T) have been associated with low circulating adiponectin levels, insulin resistance, and type 2 diabetes. We investigated whether these genetic markers are determinants of coronary artery disease (CAD) in type 2 diabetic patients. RESEARCH DESIGN AND METHODS: A total of 376 consecutive type 2 diabetic patients were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
