Article
[Proteomic analysis of proteins involved in the renal phenotype in renovascular hypertension].
Therapie - 1 Jan 2000
Pinet Florence, Poirier Florence, Fuchs Sébastien, Tharaux Pierre-Louis, Caron Michel, Corvol Pierre, Michel Jean-Baptiste, Joubert-Caron Raymonde
Abstract excerpt
Renovascular hypertension is characterised by stenosis of the renal artery and high plasma renin levels due to the recruitment of renin-producing cells along the afferent arterioles. This increase in myoepithelioid cells is mainly a result of the differentiation of existing smooth muscle cells with acquisition of a secretory phenotype. To understand the molecular mechanisms involved in this recruitment, we used...
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