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Article

Histopathological and Molecular Prognostic Markers in Medulloblastoma

1 May 2004

Abstract excerpt

Several molecular and histopathological prognostic markers have been proposed for the therapeutic stratification of medulloblastoma patients. Amplification of the c-myc oncogene, elevated levels of c-myc mRNA, or tumor anaplasia have been associated with worse clinical outcomes. In contrast, high TrkC mRNA expression generally presages longer survival. The goal of this study was to evaluate the prognostic value...

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PMID: 15198123
DOI: 10.1093/jnen/63.5.441

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