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Article

Gene expression profiling of the nervous system in murine experimental autoimmune encephalomyelitis

1 Oct 2001

Abstract excerpt

Multiple sclerosis is thought to be a polygenic disease driven by dysregulation of the immune system leading to an autoimmune response against one or several antigens of cerebral white matter tissue. Experimental autoimmune encephalomyelitis (EAE) is a mouse model that is used to study the aetiology and pathogenesis of multiple sclerosis and new therapeutic approaches. We used oligonucleotide microarrays to...

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PMID: 11571211
DOI: 10.1093/brain/124.10.1927

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