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Anti-inflammatory genes associated with multiple sclerosis: a gene expression study.

Journal of neuroimmunology - 15 Feb 2015

Perga S, Montarolo F, Martire S, Berchialla P, Malucchi S, Bertolotto A

Abstract excerpt

Multiple sclerosis (MS) is an autoimmune inflammatory disease of the central nervous system caused by a complex interaction between multiple genes and environmental factors. HLA region is the strongest susceptibility locus, but recent huge genome-wide association studies identified new susceptibility genes. Among these, BACH2, PTGER4, RGS1 and ZFP36L1 were highlighted. Here, a gene expression analysis revealed...

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Basic-Leucine Zipper Transcription Factors
Down-Regulation
Genetic Predisposition to Disease
Genome-Wide Association Study
Multiple Sclerosis

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PMID: 25670004
DOI: 10.1016/j.jneuroim.2015.01.004

Genes

BACH2
PTGER4
RGS1

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