Article
Genetic variants in SOD2, MPO, and NQO1, and risk of ovarian cancer.
Gynecologic oncology - 1 Jun 2004
Olson S H, Carlson M D A, Ostrer H, Harlap S, Stone A, Winters M, Ambrosone C B
Abstract excerpt
OBJECTIVE: One way in which parity and use of oral contraceptives may protect against ovarian cancer is by preventing inflammation and oxidative stress associated with ovulation. Since the genes superoxide dismutase (SOD2), myeloperoxidase (MPO), and NAD(P)H:quinone oxidoreductase 1 (NQO1) are involved in inflammation and oxidative stress, we investigated whether variants of these genes are associated with risk...
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