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Article

Menopausal status modifies breast cancer risk associated with the myeloperoxidase (MPO) G463A polymorphism in Caucasian women: a meta-analysis.

PloS one - 1 Jan 2012

Pabalan Noel, Jarjanazi Hamdi, Sung Lillian, Li Hong, Ozcelik Hilmi

Abstract excerpt

BACKGROUND: Breast cancer susceptibility may be modulated partly through polymorphisms in oxidative enzymes, one of which is myeloperoxidase (MPO). Association of the low transcription activity variant allele A in the G463A polymorphism has been investigated for its association with breast cancer risk, considering the modifying effects of menopausal status and antioxidant intake levels of cases and controls....

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Identifiers

PMID: 22427832
DOI: 10.1371/journal.pone.0032389
PMCID: PMC3302886

Genes

MPO

Variants

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Related research

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Menopausal status modifies breast cancer risk associated with the myeloperoxidase (MPO) G463A polymorphism in Caucasian women: a meta-analysis.PMID 22427832Read ↗

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Polymorphisms in genes related to oxidative stress (MPO, MnSOD, CAT) and survival after treatment for breast cancer.Semantic proximity Read ↗

Association between MPO-463G > A polymorphism and cancer risk: evidence from 60 case-control studies.Semantic proximity Read ↗

The possible association between the presence of an MPO -463 G > A (rs2333227) polymorphism and cervical cancer risk.Semantic proximity Read ↗

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Common genetic variants in the myeloperoxidase and paraoxonase genes and the related cancer risk: a review.Semantic proximity Read ↗

Association of myeloperoxidase polymorphism (G463A) with cervix cancer.Semantic proximity Read ↗

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