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Article

Glutathione S-transferase M1*null genotype but not myeloperoxidase promoter G-463A polymorphism is associated with higher susceptibility to endometriosis.

Molecular human reproduction - 1 Oct 2004

Hsieh Yao-Yuan, Chang Chi-Chen, Tsai Fuu-Jen, Lin Cheng-Chieh, Chen Jiun-Ming, Tsai Chang-Hai

Abstract excerpt

Glutathione S-transferase M1 (GSTM1), one member of the GST family, is responsible for metabolism of xenobiotics and carcinogens. Myeloperoxidase (MPO) plays an important role in the oxidation and activation of carcinogens and nitric oxide. Allelic variants of GSTM1 and MPO gene polymorphisms might impair detoxification function and increase the susceptibility to endometriosis. We aimed to investigate if these...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15299090
DOI: 10.1093/molehr/gah095

Genes

GSTM1
MPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Glutathione S-transferase M1*null genotype but not myeloperoxidase promoter G-463A polymorphism is associated with higher susceptibility to endometriosis.PMID 15299090Read ↗

Myeloperoxidase polymorphism, menopausal status, and breast cancer risk: an update meta-analysis.Semantic proximity Read ↗

Glutathione S-transferase M1 polymorphism and endometriosis susceptibility: a meta-analysis.Semantic proximity Read ↗

Polymorphisms of the genes encoding the GSTM1, GSTT1 and GSTP1 in Korean women: no association with endometriosis.Semantic proximity Read ↗

Glutathione-S-transferase P1 gene polymorphism and susceptibility to endometriosis.Semantic proximity Read ↗

Oxidative-Stress Related Gene Polymorphism in Endometriosis-Associated Infertility.Semantic proximity Read ↗

Association of myeloperoxidase with ovarian cancer.Semantic proximity Read ↗

Glutathione S-transferase M1 and T1 genotypes and endometriosis risk: a case-controlled study.Semantic proximity Read ↗

Glutathione S-transferase M1 and T1 gene polymorphisms and risk of endometriosis in Tunisian population.Semantic proximity Read ↗

Polymorphisms of glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) and endometriosis risk: a meta-analysis.Semantic proximity Read ↗

Genetic polymorphism in myeloperoxidase but not GSTM1 is associated with risk of lung squamous cell carcinoma in a Chinese population.Semantic proximity Read ↗

Glutathione S-transferase M1 gene polymorphism and susceptibility to endometriosis in a French population.Semantic proximity Read ↗

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