Article
Relation of MPO, MnSOD, NQO1 gene variants in endometrial carcinoma in the line of PCR-RFLP methods.
Cellular and molecular biology (Noisy-le-Grand, France) - 31 Mar 2018
Bulgurcuoglu Kuran Sibel, Iplik Elif Sinem, Cakmakoglu Bedia, Timirci Kahraman Ozlem, Iyibozkurt Ahmet Cem, Koc Arzu, Ergen Arzu, Gulec Yilmaz Seda, Isbir Turgay
Abstract excerpt
Reactive oxygen species (ROS) have been shown to be responsible for inducing DNA damage leading to mutagenesis, carcinogenesis, and cell death if the capacity of the protective antioxidant system is impaired. Endometrial carcinoma is the primary cancer type in the female genital system. The enhanced cell lipid peroxidation and impaired antioxidant enzyme activities observed in patients with endometrial cancer...
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