Article
Myeloperoxidase and CYBA genetic variants in polycystic ovary syndrome.
European journal of clinical investigation - 1 Apr 2021
Ma Wandi, Li Suiyan, Liu Hongwei, Bai Huai, Liu Qingqing, Hu Kaifeng, Guan Linbo, Fan Ping
Abstract excerpt
BACKGROUND: Oxidative stress plays a pivotal role in the pathogenesis of polycystic ovary syndrome (PCOS). Genetic variations in myeloperoxidase (MPO; G-463A) and NADPH oxidase p22phox subunit (CYBA; C242T) cause inter-individual variability in enzyme activities. Here, we investigated the associations between MPO activity and the MPO G-463A and CYBA C242T polymorphisms in Chinese women with PCOS. METHODS: This...
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