Article
Persistence of low levels of simian immunodeficiency virus in macaques that were transiently viremic by conventional testing.
Virology - 1 Jun 2004
Zhu Tuofu, Hu Shiu-Lok, Feng Feng, Polacino Patricia, Liu Huanliang, Hwangbo Yon, Learn Gerald H, Mullins James I, Corey Lawrence
Abstract excerpt
Transient SIV viremia after experimental SIV challenge has been documented. Whether SIV persists in these transiently viremic macaques remains unclear. In the present study, we applied a sensitive PCR and found persistent low levels of SIVmne infection (LLSI) (range: 0.1-5.3 SIV DNA copies/10(6) PBMC) in seven macaques that were transiently positive by conventional assays, which was 10(2)- to 10(6)-fold less than...
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