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Article

TBP, a polyglutamine tract containing protein, accumulates in Alzheimer's disease.

Brain research. Molecular brain research - 18 Jun 2004

Reid Suzanne J, van Roon-Mom Willeke M C, Wood Phil C, Rees Mark I, Owen Michael J, Faull Richard L M, Dragunow Mike, Snell Russell G

Abstract excerpt

Alzheimer's disease (AD) is characterised by extra cellular beta-amyloid (betaA) deposition, Tau-containing neurofibrillary tangles (NFTs) and progressive cortical atrophy. Abnormal protein accumulation is also a common feature of other late onset neurodegenerative diseases, including the heritable polyglutamine (polyQ) disorders such as Huntington disease (HD) and the spinocerebellar ataxias (SCAs). One of this...

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Source

Identifiers

PMID: 15193429
DOI: 10.1016/j.molbrainres.2004.03.018

Genes

TBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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