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Article

Analysis of polyglutamine-coding repeats in the TATA-binding protein in different neurodegenerative diseases.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Apr 2005

Wu Y R, Fung H C, Lee-Chen G J, Gwinn-Hardy K, Ro L S, Chen S T, Hsieh-Li H M, Lin H Y, Lin C Y, Li S N, Chen C M

Abstract excerpt

Trinucleotide repeat (TNR) expansion in the gene for TATA binding protein (TBP) has recently been described as causal for spinocerebellar ataxia type 17. The normal number of repeats has been considered to be 42 or less. An intermediate range with reduced penetrance has been assumed to be 43-47 CAA/CAG repeats. We examined this gene in 30 patients with autosomal-dominant cerebellar ataxia (ADCA), 35 patients with...

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Source

Identifiers

PMID: 15365789
DOI: 10.1007/s00702-004-0197-9

Genes

TBP
TNR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Analysis of polyglutamine-coding repeats in the TATA-binding protein in different neurodegenerative diseases.PMID 15365789Read ↗

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