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Article

Rat liver sinusoidal endothelial cell phenotype is maintained by paracrine and autocrine regulation.

American journal of physiology. Gastrointestinal and liver physiology - 1 Oct 2004

DeLeve Laurie D, Wang Xiangdong, Hu Liping, McCuskey Margaret K, McCuskey Robert S

Abstract excerpt

The phenotypic features of liver sinusoidal endothelial cells (SEC), open fenestrae in sieve plates and lack of a basement membrane, are lost with capillarization. The current study examines localization of CD31 as a marker for the dedifferentiated, nonfenestrated SEC and examines regulation of SEC phenotype in vitro. CD31 localization in SEC was examined by confocal microscopy and immunogold-scanning electron...

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Identifiers

PMID: 15191879
DOI: 10.1152/ajpgi.00017.2004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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