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Article

Differential regulation of CXCR2 trafficking by Rab GTPases.

Blood - 15 Mar 2003

Fan Guo-Huang, Lapierre Lynne A, Goldenring James R, Richmond Ann

Abstract excerpt

Intracellular trafficking of chemokine receptors plays an important role in fine-tuning the functional responses of neutrophils and lymphocytes in the inflammatory process and HIV infection. Although many chemokine receptors internalize through clathrin-coated pits, regulation of the receptor trafficking is not fully understood. The present study demonstrated that CXCR2 was colocalized with transferrin and...

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Topics

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Share to Lipoproteins, LDL
Share to Lysosomal-Associated Membrane Protein 1
Share to Lysosomal Membrane Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to rab GTP-Binding Proteins

Share to rab5 GTP-Binding Proteins

Share to rab7 GTP-Binding Proteins

Share to Receptors, Interleukin-8B

Share to Transferrin

Source

Open in PubMed Open full text

Identifiers

PMID: 12411301
DOI: 10.1182/blood-2002-07-1965
PMCID: PMC5365399

Genes

CXCR2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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