Article
Desmoplakin is required for microvascular tube formation in culture.
Journal of cell science - 1 Jul 2004
Zhou Xuan, Stuart August, Dettin Luis E, Rodriguez Gisela, Hoel Bonnie, Gallicano G Ian
Abstract excerpt
Desmoplakin (DP) is a key component of cellular adhesion junctions known as desmosomes; however, recent investigations have revealed a novel location for DP in junctions separate from desmosomes termed complexus adherens junctions. These junctions are found at contact sites between endothelial cells that line capillaries. Few studies have focused on the function of DP in de novo capillary formation...
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