Article
Plk3 functionally links DNA damage to cell cycle arrest and apoptosis at least in part via the p53 pathway.
The Journal of biological chemistry - 16 Nov 2001
Xie S, Wu H, Wang Q, Cogswell J P, Husain I, Conn C, Stambrook P, Jhanwar-Uniyal M, Dai W
Abstract excerpt
Polo-like kinase 3 (Plk3, previously termed Prk) contributes to regulation of M phase of the cell cycle (Ouyang, B., Pan, H., Lu, L., Li, J., Stambrook, P., Li, B., and Dai, W. (1997) J. Biol. Chem. 272, 28646-28651). Plk3 physically interacts with Cdc25C and phosphorylates this protein phosphatase predominantly on serine 216 (Ouyang, B., Li, W., Pan, H., Meadows, J., Hoffmann, I., and Dai, W. (1999) Oncogene 18,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.