Article
EST clustering error evaluation and correction.
Bioinformatics (Oxford, England) - 22 Nov 2004
Wang Ji-Ping Z, Lindsay Bruce G, Leebens-Mack James, Cui Liying, Wall Kerr, Miller Webb C, dePamphilis Claude W
Abstract excerpt
MOTIVATION: The gene expression intensity information conveyed by (EST) Expressed Sequence Tag data can be used to infer important cDNA library properties, such as gene number and expression patterns. However, EST clustering errors, which often lead to greatly inflated estimates of obtained unique genes, have become a major obstacle in the analyses. The EST clustering error structure, the relationship between...
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