Article
SNP detection exploiting multiple sources of redundancy in large EST collections improves validation rates.
Bioinformatics (Oxford, England) - 1 Jul 2007
Hayes Ben J, Nilsen Kjetil, Berg Paul R, Grindflek Eli, Lien Sigbjørn
Abstract excerpt
MOTIVATION: Single nucleotide polymorphism (SNP) detection exploiting redundancy in expressed sequence tag (EST) collections that arises from the presence of transcripts of the same gene from different individuals has been used to generate large collections of SNPs for many species. A second source of redundancy, namely that EST collections can contain multiple transcripts of the same gene from the same...
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