Article
Threonine for alanine substitution in the eotaxin (CCL11) gene and the risk of incident myocardial infarction.
Atherosclerosis - 1 Jul 2004
Zee Robert Y L, Cook Nancy R, Cheng Suzanne, Erlich Henry A, Lindpaintner Klaus, Lee Richard T, Ridker Paul M
Abstract excerpt
Recent studies suggest that the chemokine eotaxin may participate in atherosclerosis. Threonine (T) for alanine (A) substitution at amino acid 23 in the eotaxin gene (CCL11) has been associated with risk of developing allergic-inflammatory disorders. However, no genetic-epidemiological data are available on the risk of cardiovascular disease associated with this polymorphism. Using DNA samples collected at...
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