Article
Association of a CD18 gene polymorphism with a reduced risk of restenosis after coronary stenting.
The American journal of cardiology - 15 Nov 2001
Koch W, Böttiger C, Mehilli J, von Beckerath N, Neumann F J, Schömig A, Kastrati A
Abstract excerpt
Inflammatory mechanisms play an important role in the process of restenosis after percutaneous coronary interventions, with cell adhesion molecules, including Mac-1 (CD11b/CD18), as key mediators. A single nucleotide polymorphism, 1323C/T, located in exon 11 of the CD18 gene has been previously described, but its functional and clinical significances have not yet been studied. We assessed whether an association...
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