Article
HIV-1-specific cytotoxic T lymphocyte (CTL) responses against immunodominant optimal epitopes slow the progression of AIDS in China.
Current HIV research - 1 Jun 2008
Zhai Song, Zhuang Yan, Song Yang, Li Shu, Huang Dedong, Kang Wenzhen, Li Xinhong, Liao Qi, Liu Yanhou, Zhao Zhongfang, Lu Yichen, Sun Yongtao
Abstract excerpt
To assess the immunodominance patterns of HIV-1-specific cytotoxic T lymphocyte (CTL) responses and the contribution of these responses against the peptides scanning optimal epitopes in chronic infection, we test the HIV-1-specific CTL responses against a panel of 413 overlapping peptides spanning HIV-1 Asian B sequence, including 147 peptides corresponding to optimal clade B epitopes in 49 chronically HIV-1...
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