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Article

Maximum-likelihood estimation of haplotype frequencies in nuclear families.

Genetic epidemiology - 1 Jul 2004

Becker Tim, Knapp Michael

Abstract excerpt

The importance of haplotype analysis in the context of association fine mapping of disease genes has grown steadily over the last years. Since experimental methods to determine haplotypes on a large scale are not available, phase has to be inferred statistically. For individual genotype data, several reconstruction techniques and many implementations of the expectation-maximization (EM) algorithm for haplotype...

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PMID: 15185400
DOI: 10.1002/gepi.10323

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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