Article
The yeast genes, ARL1 and CCZ1, interact to control membrane traffic and ion homeostasis.
Biochemical and biophysical research communications - 2 Jul 2004
Love Sherie L, Manlandro Cara Marie A, Testa Christopher J, Thomas Anne E, Tryggestad Kari-Elise, Rosenwald Anne G
Abstract excerpt
The yeast ARL1 gene, encoding a guanine-nucleotide binding protein of the Arf-like family, exhibits a synthetic genetic interaction with CCZ1. An arl1 Delta ccz1 Delta double mutant was viable but grew slowly, was more sensitive to caffeine, Ca(2+), Zn(2+), and hygromycin B than either single mutant, and had a more severe vacuolar protein sorting phenotype. Overexpression of ARL1 did not suppress ccz1 Delta...
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