Article
Multiple functions of the vacuolar sorting protein Ccz1p in Saccharomyces cerevisiae.
Biochemical and biophysical research communications - 1 Apr 2005
Hoffman-Sommer Marta, Migdalski Andrzej, Rytka Joanna, Kucharczyk Róza
Abstract excerpt
The CCZ1 (YBR131w) gene encodes a protein required for fusion of various transport intermediates with the vacuole. Ccz1p, in a complex with Mon1p, is a close partner of Ypt7p in the processes of fusion of endosomes to vacuoles and homotypic vacuole fusion. In this work, we exploited the Ca(2+)-sensitivity of the ccz1Delta mutant to identify genes specifically interacting with CCZ1, basing on functional multicopy...
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