Article
Study on the expression and mutation of human telomeric repeat binding factor (hTRF1) in 10 malignant hematopoietic cell lines.
Journal of Zhejiang University. Science. B - 1 Dec 2005
Sun Jie, Huang He, Zhu Yuan-yuan, Lan Jian-ping, Li Jing-yuan, Lai Xiao-yu, Yu Jian
Abstract excerpt
OBJECTIVE: Detecting the expression and mutation of human telomeric repeat binding factor (hTRF1) in 10 malignant hematopoietic cell line cells on the base of determining its genomic structure and its four pseudogenes to clarify if hTRF1 mutation is one of the factors of the activation of telomerase. METHODS: hTRF1cDNA sequences were obtained from GenBank, its genome structure and pseudogenes were forecasted by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
