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Article

Genetic variation in telomeric repeat binding factors 1 and 2 in aplastic anemia.

Experimental hematology - 1 May 2006

Savage Sharon A, Calado Rodrigo T, Xin Zhong-Tao, Ly Hinh, Young Neal S, Chanock Stephen J

Abstract excerpt

OBJECTIVE: Abnormal telomere shortening has been observed in a subset of individuals with aplastic anemia (AA). We hypothesized that genetic variation in two genes critical in telomere biology, TERF1 and TERF2, could be a risk factor for AA. METHODS: The proximal promoter and all coding regions of TERF1 and TERF2 were sequenced in 47 individuals with acquired AA. Regions with genetic variation were sequenced in...

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Identifiers

PMID: 16647572
DOI: 10.1016/j.exphem.2006.02.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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