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[Development of human myeloid leukemia-like phenotype in NUP98-PMX1 transgenic mice].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 May 2004

Wang Yang, Gu Ming-min, Tan Yi, Lu Shun-yuan, Wang Long, Kong Hui, Sun Yue-ping, Lu Zhen-yu, Chen Sai-juan, Wang Zhen-yi, Wang Zhu-gang

Abstract excerpt

OBJECTIVE: In order to investigate the leukemogenic potential of NUP98-PMX1 fusion gene in vivo. METHODS: NUP98-PMX1 transgenic mice were generated, in which the fusion gene was driven by hCG promoter and expressed in myeloid cells at early stage of differentiation. Molecular cloning technology was used to construct NUP98-PMX1 transgenic plasmid. The genotype and phenotype of the NUP98-PMX1 transgenic mice were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15182531

Genes

NUP98

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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