Article
[Mutations of the p53 gene in hematologic neoplasms].
Nihon rinsho. Japanese journal of clinical medicine - 1 Jun 1992
Mori N, Mizoguchi H
Abstract excerpt
The p53 gene encodes a nuclear phosphoprotein and is now considered as a tumor suppressor gene. Mutations of the p53 gene have frequently been observed in several types of solid tumors and are believed to be implicated in the development of these tumors. Recent studies have shown that the p53 gen...
Topics
- Blast Crisis
- Genes, Tumor Suppressor
- Genes, p53
- Humans
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive
- Mutation
