[P53 genes and malignant hematologic diseases].

Article

[P53 genes and malignant hematologic diseases].

Bulletin du cancer - 1 Aug 1993

Jonveaux P

Abstract excerpt

Mutations of the P53 tumor suppressor gene represent the most common genetic lesion in human solid tumors. In hematological malignancies, P53 alterations are detected in the evolution of the chronic myelogenous leukemia to myeloid blast crisis. P53 mutations were also found to be associated with...

Topics

Gene Expression Regulation, Neoplastic
Genes, p53
Humans
Lymphoproliferative Disorders
Mutation

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