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Article

Molecular landscape of acute promyelocytic leukemia at diagnosis and relapse

24 Mar 2017

Abstract excerpt

Acute promyelocytic leukemia (APL) occurs in about 5–30% of adult de novo AML and is characterized by the presence of the chromosomal translocation t(15;17)(q24;q21). The resulting PML-RARA chimeric gene involves the retinoic acid receptor alpha-(RARA) gene on chromosome 17 and the PML gene, a

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PMID: 28341736
DOI: 10.3324/haematol.2016.162206

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