Article
VHL mutations in renal cell cancer: does occupational exposure to trichloroethylene make a difference?
Toxicology letters - 15 Jun 2004
Brauch Hiltrud, Weirich Gregor, Klein Bettina, Rabstein Sylvia, Bolt Hermann M, Brüning Thomas
Abstract excerpt
Occupational exposures have long been suspected to play a role in the incidence of renal cell carcinoma (RCC). Especially, the carcinogenicity of the industrial solvent trichloroethylene (TCE) has been controversially debated, both with respect to the epidemiological and the molecular studies. In order to further elucidate this issue, it appeared important to compare suitable RCC patient groups, i.e., TCE-exposed...
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