Article
[Prevention of renal carcinoma: the nutri-genetic approach].
Journal de la Societe de biologie - 1 Jan 2000
Junien C, Dupret J M, Gallou C, Longuemaux S, Richard S, Saquet C, Krishnamoorty R, Delomenie C, Droz D, Bouvier R, Chauveau D, Joly D, Grunfeld J P, Chretien Y, Mejean A, Beroud C
Abstract excerpt
The development of renal cell carcinoma (RCC) has been associated with both genetic and environmental factors, with somatic and germline mutations in the von Hippel-Lindau (VHL) tumor suppressor gene and with tobacco smoking, obesity, long term exposure to some nutrients, pollutants, and industrial solvents such as trichloroethylene. Intra and interfamilial variability of expression of germline mutations in the...
Topics
- Acetylation
- Arylamine N-Acetyltransferase
- Biotransformation
- Carcinogens, Environmental
- Carcinoma, Renal Cell
- Cytochrome P-450 CYP1A1
- Cytochrome P-450 Enzyme System
- DNA Mutational Analysis
- DNA, Neoplasm