Article
[The role of HLA genes: from autoimmune diseases to COVID-19].
Problemy endokrinologii - 1 Sept 2020
Troshina Ekaterina A, Yukina Marina Yu, Nuralieva Nurana F, Mokrysheva Natalia G
Abstract excerpt
Genes of HLA system (Human Leukocyte Antigen) play an essential role in the normal functioning of the immune system. There are three classes of genes: I, II, and III. The function of HLA molecules class I is to present antigens of peptides from the cytoplasm to T-lymphocytes on the cell surface, and class II - to present antigens of peptides from the extracellular space. In the classical view, the pathological...
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