Article
Comparative high-resolution analysis of linkage disequilibrium and tag single nucleotide polymorphisms between populations in the vitamin D receptor gene.
Human molecular genetics - 1 Aug 2004
Nejentsev Sergey, Godfrey Lisa, Snook Hywel, Rance Helen, Nutland Sarah, Walker Neil M, Lam Alex C, Guja Cristian, Ionescu-Tirgoviste Constantin, Undlien Dag E, Rønningen Kjersti S, Tuomilehto-Wolf Eva, Tuomilehto Jaakko, Newport Melanie J, Clayton David G, Todd John A
Abstract excerpt
A genome-wide map of single nucleotide polymorphisms (SNP) and a pattern of linkage disequilibrium (LD) between their alleles are being established in three main ethnic groups. An important question is the applicability of such maps to different populations within a main ethnic group. Therefore, we have developed high-resolution SNP, haplotype and LD maps of vitamin D receptor gene region in large samples from...
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