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Article

Flow cytometric assay for genotyping cytochrome p450 2C9 and 2C19: comparison with a microelectronic DNA array.

American journal of pharmacogenomics : genomics-related research in drug development and clinical practice - 1 Jan 2004

Pickering Jerry W, McMillin Gwendolyn A, Gedge Friederike, Hill Harry R, Lyon Elaine

Abstract excerpt

INTRODUCTION: Cytochrome p450 (CYP) 2C9 and 2C19 metabolize a wide range of therapeutically important drugs. Genetic polymorphisms in the CYP2C9 and CYP2C19 genes result in variations in drug response. To correlate the dose required for therapeutic drug efficacy with genotype, accurate and reliable methods for detecting single nucleotide polymorphisms (SNPs) of CYP2C9 and CYP2C19 are required. STUDY DESIGN: We...

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Identifiers

PMID: 15174901
DOI: 10.2165/00129785-200404030-00007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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