Article
[A new, rapid and robust genotyping method for CYP2C9 and MDR1].
Annales de biologie clinique - 1 Jan 2000
Verstuyft C, Morin S, Yang J, Loriot M-A, Barbu V, Kerb R, Brinkmann U, Beaune P, Jaillon P, Becquemont L
Abstract excerpt
Single nucleotide polymorphisms (SNPs) can significantly affect human phenotypes. Detection of allelic variant carriers has become a major goal for clinical pharmacologists in order to study phenotype-genotype relationships. However, there is a crucial need for rapid, and validated pharmacogenetic tests. The aim of the study was to validate a new fluorescence PCR strategy for cytochrome P450 2C9 (CYP2C9) and...
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