Systematic micro-array based identification of placental mRNA in maternal plasma: towards non-invasive prenatal gene expression profiling

Abstract excerpt

The discovery of fetal DNA in the plasma of pregnant women1 has led to the development of promising approaches for non-invasive prenatal diagnosis.2–6 However, as fetal and maternal DNA species co-exist in maternal plasma, these DNA based diagnostic applications depend largely on the use of genetic markers that would allow the discrimination between fetal and maternal DNA (for example, the Y chromosome of a male...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Fetal and Pediatric Neurological Disorders
• Share to Molecular Biology Techniques and Applications
• Share to Prenatal Screening and Diagnostics