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Detection of Chromosome 21-encoded mRNA of Placental Origin in Maternal Plasma

1 Sept 2003

Abstract excerpt

BACKGROUND: mRNA of placental origin (i.e., human placental lactogen and beta-human chorionic gonadotropin) has been demonstrated to be easily detectable in maternal plasma. We tested whether detection of chromosome 21-encoded mRNA of placental origin is possible in maternal plasma obtained during the first trimester. METHODS: Plasma samples were obtained from pregnant women between weeks 9-13 of pregnancy. RNA...

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Share to Gestational Trophoblastic Disease Studies
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PMID: 12928224
DOI: 10.1373/49.9.1445

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