Article
Maternal plasma RNA sequencing for genome-wide transcriptomic profiling and identification of pregnancy-associated transcripts.
Clinical chemistry - 1 Jul 2014
Tsui Nancy B Y, Jiang Peiyong, Wong Yuen Fei, Leung Tak Y, Chan K C Allen, Chiu Rossa W K, Sun Hao, Lo Y M Dennis
Abstract excerpt
BACKGROUND: Analysis of circulating RNA in the plasma of pregnant women has the potential to serve as a powerful tool for noninvasive prenatal testing and research. However, detection of circulating RNA in the plasma in an unbiased and high-throughput manner has been technically challenging. Therefore, only a limited number of circulating RNA species in maternal plasma have been validated as pregnancy- and...
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