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Measuring circulating placental RNAs to non-invasively assess the placental transcriptome and to predict pregnancy complications

13 Oct 2016

Abstract excerpt

Circulating nucleic acids have revolutionized prenatal diagnosis in the last decade, allowing non-invasive screening for single gene or chromosomal defects using a single sample of maternal blood. In addition to DNAs, RNAs from the placenta are released into the maternal blood from early in pregnancy and may reflect changes in gene expression occurring within the placenta. Measuring circulating RNA may therefore...

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PMID: 27711965
DOI: 10.1002/pd.4934

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